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YARUMAL, - AUGUST 18 - Alirio sits in his living room with his son Alexis, 6, snuggles in and his wife Marta. Alirio, 42, is a coffee farmer who is also a participant in the University of Antioquia study who lives near Yarumal. The study, lead by Dr. Francisco Lopera, a behavioural neurologist at Medellin's University of Antioquia, researches a local family tree with a genetic mutation that causes early-onset Alzheimer's disease. The Colombian family's genetic curse may be the world's best hope for an Alzheimer's cure. In that family tree researchers have the perfect group to study the disease and have now begin a clinical trial to see if they have a medication that might be able to delay onset. in Medellin. (Steve Russell/Toronto Star via Getty Images)

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A moving story reveals hidden human cost of drug trials

Drug trials are vital to medicine, but what of those taking part? Jennie Erin Smith's moving new book about what happened in a rural community hit by early-onset Alzheimer's disease gives them a voice

Culture

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Do Ozempic and Wegovy really cause hair loss?

Analysis

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Does aspirin have potential as an anti-cancer drug?

Analysis

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Pregnancy’s lasting effects on different parts of the body revealed

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Mandatory Credit: Photo by Ute Grabowsky/imageBROKER/Shutterstock (13880334oy) Pack of Ozempic, antidiabetic drug for weight control, taken in a pharmacy in Niesky, 13.04.2023., Niesky, Germany Various 23aecabfaa

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The Ozempic era is only just beginning

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GLP-1 drugs are only the start – the powerful drugs to expect next

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GLP-1 drugs are only the start – the powerful drugs to expect next

Features

What do GLP-1 drugs really tell us about the brain's reward system?

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What do GLP-1 drugs really tell us about the brain's reward system?

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Why exercise is more important than ever when taking weight-loss drugs

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Why exercise is more important than ever when taking weight-loss drugs

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Microdosing weight-loss drugs is on the rise – but does it work?

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Microdosing weight-loss drugs is on the rise – but does it work?

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The unexpected impacts of a society transformed by weight-loss drugs

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The unexpected impacts of a society transformed by weight-loss drugs

Drugs like Ozempic and Wegovy have the power to block the forces driving obesity, but the knock-on societal effects may not necessarily be so positive

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The 13 drugs and supplements that could slow brain ageing

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Health scares for a new generation must be tackled with solid science

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Life

Chimps and bonobos relieve social tension by rubbing their genitals

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The alarming rise of colorectal cancer diagnoses in people under 50

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