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Motor made from bacteria parts is one of the smallest ever built

The natural motors that power tail-like appendages in bacteria seem to have a single evolutionary origin, allowing parts from different species to be combined to create a tiny new engine
An illustration showing the natural motor of a bacterium
RAMON ANDRADE 3DCIENCIA/SCIENCE PHOTO LIBRARY

A living motor made by combining different parts from bacteria is one of the smallest ever built, and could one day power tiny robots.

Many types of bacteria are propelled by natural motors that power the rotation of tail-like flagella. These rotary pumps, known as stators, are among the world’s oldest and smallest wheels, being thought to have evolved billions of years ago.

Every bacteria species with this kind of pump follows the same 5:2 design of five small components built around two protein compounds in the middle that act like an axle. This is why at the University of New South Wales, Australia, and his colleagues decided to use gene editing to combine parts of motors from two different species of bacteria, Escherichia coli and Vibrio alginolyticus.

The team tried 14 different combinations of parts before finding one that worked. The resulting “chimeric microbe motor” is a mere 6 nanometres in diameter and generates electricity to drive its microscopic wheels using sodium in a solution of salt water. “Essentially, we have hacked into the bacteria’s engine,” says Baker.

While other researchers have built smaller, molecule-scale motors, Baker says his team’s is the first to be powered independently, in a step towards a “bacteria-based chimera robot”.

“We are engineering a nano-scale motor that can go where we want and when we want,” he says. “The next step is to have that hacked motor carry some cargo, so we can deliver that cargo on demand.”

at Texas A&M University compares the result to swapping the spark plugs in a car with those of a lawnmower and finding they still work. “That suggests the motors of the car and lawnmower motor were based on design principles embodied in an original internal combustion engine that was modified to perform different functions,” he says. “This work provides the first experimental evidence that corroborates the hypothesis that all 5:2 electric motors diverged from an ancient common ancestor to perform very different functions in bacteria.”

Journal reference:

Journal of Bacteriology

Topics: Bacteria