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Chemist Lee Cronin is building an alien to work out why life exists

Lee Cronin is making a vast chemical robot – and an alien – to find out why life exists and if we can detect it on other worlds

Lee Cronin

As a child, what did you want to do when you grew up?

From about 7 years old, I was always taking stuff apart to build new things like lasers and computers, but they never worked. I wanted to know why, so I dreamed of being a scientist.

Were you good at science at school?

I wanted to be, but I struggled to concentrate and messed around a lot.

Explain what you do in one paragraph.

I’m a chemistry professor who loves inventing stuff to understand things. Right now, we are trying to build an alien life form, to control chemistry with computers and to see if we can make a chemical computer and perhaps even a brain.

And in one sentence?

My entire life, I’ve been looking for patterns in nature and to understand why life exists and how chemistry makes information – that dream follows me around in everything I do.

What does a typical day involve?

There’s no typical day, but when I’m not travelling, I spend a lot of time talking with my team, dreaming up new experiments, writing manuscripts and applying for funding. In the evening, I go for a run and spend time with my family, and I’m often in my home laboratory/workshop building stuff.

What do you love most about what you do? And what’s the worst part?

I love dreaming up new ideas for experiments and making new discoveries. There is no worst part, but I often find it hard to express new ideas in a way that anybody can understand.

What’s the most exciting thing you’re working on right now?

We’re building a modular chemical robot called the chemputer, inspired by the scale of the Large Hadron Collider, but exploring chemistry and the origin of life instead. We’ve already used it to make important molecules like drugs automatically just from computer code and chemicals.

If you could send a message back to yourself as a kid, what would you say?

I’d reassure myself that feeling stupid is OK and that I should enjoy my confusion more.

“I’d reassure my childhood self that feeling stupid is OK”

What scientific development do you hope to see in your lifetime?

I’d love it if we discovered a new type of life elsewhere in the universe.

Which discovery do you wish you’d made yourself?

The transistor.

What’s the best piece of advice anyone ever gave you?

Seek criticism widely and address it all.

What’s the best thing you’ve read or seen in the past 12 months?

Superheavy by Kit Chapman. I love all science but I am a chemist at heart. Reading this book about making the heavy elements was inspirational.

If you could have a long conversation with any scientist, living or dead, who would it be?

I would love to get computing pioneer John von Neumann and synthetic chemist Ben Feringa together to discuss how to make molecular self-constructing machines.

How useful will your skills be after the apocalypse?

I might be able to build computers or lasers that work, finally.

OK, one last thing: tell us something that will blow our minds…

I’ve invented a theory that might be able to help us identify alien signatures, those of life forms in the lab, in the solar system and on exoplanets. This theory might also unlock how we build new life in the lab and explain the origin of life.


Lee Cronin is Regius Chair of Chemistry at the University of Glasgow, UK

Topics: Alien life / Chemistry