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Why cuts in your mouth heal 10 times faster than skin wounds

Wounds in the mouth really do heal much faster than cuts to the skin, and it may be because mouth cells are genetically primed for healing
Don’t worry, it’ll get better soon
Andriy Popov / Alamy

It’s true – wounds in the mouth really do heal much faster than cuts to the skin. A study has discovered that the lining of the mouth is permanently primed for healing. The finding could lead to new ways to improve wound-healing elsewhere in the body.

of the University of California at San Diego and his team made small wounds in the mouths and on the upper arms of 30 volunteers, and tracked how well and quickly they healed.

The mouth wounds rapidly closed and healed scarlessly, some taking only a week to fully repair themselves. But the width of the skin wounds had scarcely changed after two weeks.

“The oral wounds healed approximately 5 to 10 times faster than skin wounds,” says Gutkind.

Biopsies revealed that networks of healing genes are permanently active or on standby in the cells of the mouth lining, but not in skin cells. When the team genetically engineered mice to activate these networks in their skin, their skin was capable of healing wounds slightly faster.

“Our results provide clues about the biology of wound healing, and offer a biological blueprint for developing novel therapeutics for faster wound healing,” says of the US National Institute of Arthritis and Musculoskeletal and Skin Disease in Bethesda, Maryland.

Science Translational Medicine

Read more: Daytime injuries heal twice as fast as wounds sustained at night