THE futility of arguing that HIV does not cause AIDS, a theory that the South
African government is controversially flirting with, has been underlined by new
research in the US. American scientists have gone back to first principles to
show that a related virus definitively causes AIDS symptoms in monkeys.
Despite the overwhelming epidemiological and laboratory evidence to the
contrary, Peter Duesberg, a molecular biologist at the University of California
at Berkeley, says it鈥檚 impossible to confirm that HIV causes AIDS. South African
politicians caused an uproar with their recent tacit support of his theory
(快猫短视频, 29 April, p 14).
Specifically, Duesberg points out that medical science has failed to satisfy
鈥淜och鈥檚 postulates鈥. According to this old maxim, you only prove an agent causes
a disease if you can show that it can cause symptoms in isolation.
Ruth Ruprecht of Harvard Medical School and her colleagues isolated the pure
DNA form of the SIV virus, HIV鈥檚 close relative that causes AIDS in monkeys.
Researchers believe that HIV1 evolved from SIV only recently. This naked viral
DNA was then injected into six infant and six adult macaques. All twelve animals
made antibodies to the virus. Three of the infants and one of the adult monkeys
died from AIDS.
Advertisement
鈥淚 hope that Peter Duesberg is listening to this,鈥 Ruprecht told the
conference. Short of deliberately injecting purified HIV into humans, it is 鈥渁s
near as we are ever going to get to proving HIV causes AIDS鈥, she says, adding
that although SIV is different from HIV, 鈥渁ny molecular biologist of any value
could see they are related viruses causing the same sort of disease鈥.